Sildenafil citrate is a generic medicine prescribed in cases of erectile dysfunction. This medication acts specifically on the PDE-5 enzyme, inducing blood flow to the penis. It is equivalent to the effects of patented sildenafil citrate. For what is considered an effective generic drug against impotence. Sildenafil citrate acts within sixty minutes of its intake and its effect last up to 4 hours. However, the erection it produces will be associated with sexual stimuli that incite sexual desire.
Sildenafil citrate constituted a revolution in the treatment of erectile dysfunction. Effectively, Sildenafil far exceeded the efficiency of other therapies against impotence. Leaving behind the radical treatments where androgens were administered and intracavernous injections and even intra-lateral injections of prostaglandins.
Efficacy of Sildenafil Citrate:
Sildenafil citrate stimulates the erection only in patients who have not undergone surgical or other alterations on the nerve endings associated with an erection. Since physiologically the erection is associated with the release of nitric oxide in the corpus cavernosum of the penis. Then the action of sildenafil citrate works directly on the muscle of the corpus cavernosum, making possible the flow of blood and therefore the erection. Patients have reported the decrease in refraction of the penis after ejaculation when they have ingested sildenafil.
In the journal of the Ibero-American Society of Scientific Information (SIIC), scientific studies have been published showing the questionnaire called “Index of Erectile Dysfunction” (IIEF). In it, five domains have been delimited:
- Sexual desire
- Sexual satisfaction
Applying the questionnaire to a significant sample of patients with erectile dysfunction of an organic or psychogenic nature, it was concluded that the intake of the 50 mg sildenafil citrate average dose resulted in satisfactory responses for a rate higher than 65% of the cases.
In another range are patients who presented erectile dysfunction caused by neurogenic causes. Patients undergoing prostate operations presented dissimilar responses, associated with the anatomopathological stages of the lesion. The radicality of the surgery and the resulting neurological affectations affect the efficiency of sildenafil citrate therapy. Recall that the effect of sildenafil citrate works on the muscle of the corpus cavernosum. This muscle will only respond with an erection if the associated nerves are not atrophied.
Precautions in the use of Sildenafil Citrate:
Before using any medication, it is necessary to call your doctor to be prescribed. In the case of Sildenafil Citrate, the levels of precaution are increased, due to their incidence in the blood flow. The doctor must perform a thorough examination of the patient and build a very complete medical history. To do this, it must emphasize potential problems of cardiovascular, circulatory, penile malformations, anemia, cancer, liver and kidney conditions, ocular hypertension among others. A widely known risk factor is the concomitant use of Sildenafil Citrate and nitrates – nitroglycerin, cimetidine, erythromycin – The combination of both drugs drastically decreases blood flow in the coronary arteries, as a consequence of the vasodilator effect of Sildenafil Citrate. This can cause death.
The use of Sildenafil Citrate has been associated on many occasions with cardiovascular events. Indeed, from vascularbrain accidents, cardiac arrhythmias, myocardial infarction to ischemic attacks have been reported, after having enjoyed sexual activity using Sildenafil. However, there is no conclusive scientific evidence to indicate that the appropriate use of Sildenafil has been the trigger for the aforementioned events. However, the use of Sildenafil Citrate in patients with cardiovascular risk factors is not recommended. In any case, your doctor will indicate the starting dose that usually begins with minimum doses, preceded by physical and laboratory tests that will indicate your health status.
Presentation and dose of Sildenafil Citrate:
The presentation of Sildenafil Citrate varies according to the laboratory. There are presentations that vary between 20 mg, 50 mg and 100 mg. Other laboratories present formulations of 0.8 mg / ml and 10 mg / ml. The administration of sildenafil citrate is oral. Varying its formats from coated capsules, chewable tablets and even sublingual pills Consequently, it is essential that you consult your doctor to prescribe what is the most appropriate dose for you.
Among the best known brands in the market are:
- SILDENAFILO KRKA
- RATIOPHARM among many others.
Where to buy Sildenafil Citrate:
Sildenafil Citrate is available in physical pharmacies and online pharmacies. However, remember the recommendations of the WHO World Health Organization, referring to the purchase of medicines online